Endocrine Abstracts

Introduction: Vitamin D deficiency is observed across all age groups and both sexes. Moreover vitamin D deficiency is common in elderly especially along elderly patients. Elderly people are prone to develop of vitamin D deficiency caused by various factors such as deceased dietary intake, impaired intestinal absorption, reduced sunlight exposure, impaired skin synthesis as well as impaired hydroxylation in the liver and kidneys. Vitamin D deficiency may leads to rickets, osteo...

Introduction: Pentraxin-3 (PTX3) is an acute-phase reactant that shares structural and functional homology with C-reactive protein (CRP). However, unlike CRP, which is synthesized mainly in the liver, PTX3 is produced at the site of inflammation. It has been suggested that PTX3 plays the same role in the periphery that CRP does in circulation. PTX3 may represent a rapid marker for local inflammation.Methods: Fifty three patients with stable coronary arte...

IntroductionInadequate low serum of 25(OH) vitamin D leads to skeletal effect (rickets, osteoporosis, osteomalacia) and furthermore exhibits nonskeletal effects – increase the risk of cardiovascular diseases, type 2 diabetes, mental illness and many others. Vitamin D deficiency is associated with a severe morbidity burden and low functional performance among elderly patients. A long length-of-stay (LOS) among elderly patients is related to revere mo...

Introduction: It is well known that DHEA and DHEA-S has and impact on lipid metabolism, cardiovascular system and others. De Castro et al. showed that cortisol/DHEA-S ratio was an independent predictor of long-term mortality in patients with sepsis. Chronic inflammation is an important factor in cardiovascular diseases development that reduce quality and life expectancy. CVDs are more common in patients with adrenal incidentaloma than in general population. Literature data on ...

Introduction: Polycystic ovary syndrome is complex endocrine disorders, characterized by ovulatory dysfunction, hyperandrogenism and polycystic ovarian morphology. Those are lipid abnormalities, hyperinsulinemia, insulin resistance, impaired glucose metabolism, type 2 diabetes mellitus, metabolic syndrome, hyperandrogenism, oxidative stress and infertility. The visceral adiposity index (VAI) is a reliable marker of adipose tissue abnormalities in women with PCOS. A body shape ...

Introduction: Polycystic ovary syndrome (PCOS) contributes to endocrine and metabolic complications. Cardiovascular disease (CVD) is a leading cause of mortality and morbidity worldwide. Identification of the subpopulations with a higher risk of developing CVD and lipid metabolic disorders is crucial, particularly in PCOS patients.Aim: The aim of this study was to investigate the usefulness of new anthropometric indices such as BAI, VAI, LAP, BRI, ABSI a...

Introduction: The prevalence of obesity in elderly population increased. Obesity leads to increased morbidity and mortality as well as worsens quality of life in older individuals. Body-mass index (BMI) is the most widely used adiposity index. BMI correlates with body fatness but this index does not account for fat mass versus fat-free mass. Recently a new index of body adiposity the body adiposity index (BAI) was introduced. This novel index correlates well (in comparison to ...

Introduction: Chronic inflammation is an important factor in type 2 diabetes and cardiovascular diseases development. Studies demonstrate that body fat, estimated by anthropometric indicators, correlates with inflammation indicators in chronic diseases. Ipso facto, it seems reasonable to suppose, that there would also be a correlation between anthropometric parameters and both, old and new inflammation indicators in patients with non-functioning adrenal incidentalomas.<p c...

Introduction: Vitamin D has pleiotropic effect on human body. Several studies showed that vitamin D deficiency has an influence on inflammation status in endocrine diseases (PCO-S, Graves disease, autoimmune endocrine disorders) and could reflect body fat tissue contain. Both, resistin and leptin, show pro-inflammatory effect.Aim: The aim of the study was to asses resistin and leptin serum concentration and its relationship with 25-OH vitamin D concentra...

Adropin, hormone playing an important role in carbohydrates and lipids metabolism, improves mainly the glucose homeostasis. It could also play a protective role in pathogenesis and development of cardiovascular diseases. The purpose of the study was to assess the adropin concentration and some parameters of nutritional status (BMI, WHtR, BAI, VAI) as well as biochemical parameters (fasting glucose and insulin, and lipid profile). 25 patients (84% of group was women, n...